Exploring transcriptional switches from pairwise, temporal, and population RNA-Seq data using deepTS
Transcriptional switch (TS) is a widely observed phenomenon caused by changes in the relative expression of transcripts from the same gene, in spatial, temporal, or other dimensions. TS has been associated with human diseases, plant development, and …
A bioinformatics framework for comprehensive assembly and functional annotation
A widely used approach in transcriptome analysis is the alignment of short reads to a reference genome. However, owing to the deficiencies of specially designed analytical systems, short reads unmapped to the genome sequence are usually ignored, …